Griffipavixanthone - CAS 219649-95-3

Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. It can inhibit tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer.

ROS, Raf, ERK, MEK, Apoptosis, Caspase

Proteases/Proteasome, Apoptosis, Immunology/Inflammation, MAPK

219551

C36H28O12

652.6

CC1=C[C@H]2[C@H]([C@@H](c3c2c2c(oc4cc(O)cc(O)c4c2=O)c(O)c3O)c2cc(O)c(O)c3oc4cc(O)cc(O)c4c(=O)c23)C(C)(C)C1

-20°C

Ice Packs

Natural Product