GS-443902 - CAS 1355149-45-9

Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.

Drug Metabolite, DNA/RNA Synthesis, HCV Protease, Nucleoside Antimetabolite/Analog, SARS-CoV, RSV

Metabolism, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Proteases/Proteasome, Microbiology/Virology

1355095

C12H16N5O13P3

531.2

Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N

-20°C

Ice Packs

Small Compound