GS-443902 trisodium - CAS 1355050-21-3

GS-443902 trisodium (GS-441524 triphosphate trisodium), the active triphosphate metabolite of Remdesivir (GS-5734), serves as a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), displaying inhibitory concentrations (IC50) of 1.1 μM for RSV RdRp and 5 μM for HCV RdRp.

Others, SARS-CoV, DNA/RNA Synthesis, Drug Metabolite, HCV Protease, RSV

DNA Damage/DNA Repair, Proteases/Proteasome, Cell Cycle/Checkpoint, Others, Microbiology/Virology, Metabolism

1355026

C12H16N5O13P3.xNa

C(#N)[C@]1(O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)[C@H]1O)C=2N3C(=CC2)C(N)=NC=N3.[Na]

-20°C

Ice Packs

Small Compound