GS-493 - CAS 1710337-31-7

GS-493, a highly specific protein tyrosine phosphatase SHP2 (PTPN11) inhibitor, exhibits remarkable potency with an IC50 of 71 nM. It displays 29- and 45-fold greater affinity towards SHP2 compared to its related counterparts, SHP1 and PTP1B, respectively. In addition, GS-493 impedes both cellular motility and growth of cancer cells, portraying promising antitumor effects.

Others, Phosphatase

Metabolism, Others

1710299

C21H14N6O8S

510.44

OS(=O)(=O)c1ccc(N\N=C2/C(=O)N(N=C2c2ccc(cc2)N(=O)=O)c2ccc(cc2)N(=O)=O)cc1 |c:14|

-20°C

Ice Packs

Small Compound