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GSK-1070916 - CAS 942918-07-2

GSK-1070916 - CAS 942918-07-2

MF-0017554-01

$40.65 USD
$40.65 USD
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Product Details

  • Bioactivity

    GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.

  • Target

    AMPK, Tie-2, Aurora Kinase, FLT, Apoptosis

  • Related Pathways

    Apoptosis, Chromatin/Epigenetic, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Angiogenesis, PI3K/Akt/mTOR signaling

  • CAS Number

    942918-07-2

  • Purity

    0.9973

  • Molecular Formula

    C30H33N7O

  • Molecular Weight

    507.63

  • SMILES

    CCn1cc(c(n1)-c1ccc(NC(=O)N(C)C)cc1)-c1ccnc2[nH]c(cc12)-c1cccc(CN(C)C)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound