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Molfinity

GSK-114 - CAS 1301761-96-5

GSK-114 - CAS 1301761-96-5

SKU:MF-0094662-01

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  • Bioactivity

    GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.

  • Target

    MAPK, Others

  • Related Pathways

    Others, MAPK

  • CAS Number

    1301660

  • Purity

    0.9966

  • Molecular Formula

    C19H23N5O4S

  • Molecular Weight

    417.48

  • SMILES

    CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound