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GSK-114 - CAS 1301761-96-5
GSK-114 - CAS 1301761-96-5
SKU:MF-0094662-01
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$35.41 USD
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$35.41 USD
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Product Details
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Bioactivity
GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.
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Target
MAPK, Others
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Related Pathways
Others, MAPK
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CAS Number
1301660
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Purity
0.9966
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Molecular Formula
C19H23N5O4S
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Molecular Weight
417.48
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SMILES
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound