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Molfinity
GSK-25 - CAS 874119-56-9
GSK-25 - CAS 874119-56-9
SKU:MF-0011836-01
Regular price
$39.15 USD
Regular price
$25.35 USD
Sale price
$39.15 USD
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Product Details
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Bioactivity
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested) .
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Target
MTOR, ROCK, S6 Kinase
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Related Pathways
Stem Cells, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, MAPK
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CAS Number
874119-56-9
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Purity
0.9914
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Molecular Formula
C24H16Cl2F2N6O
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Molecular Weight
513.33
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SMILES
CC1=C(C(N=C(N1)c1ccnc(Cl)c1)c1ccc(Cl)cc1F)C(=O)Nc1cc2cn[nH]c2cc1F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound