GSK-2807 free base - CAS 2245255-65-4

GSK2807 is a potent and selective, SAM-competitive inhibitor of SMYD3 (Ki = 14 nM) . GSK2807 bridges the gap between the SAM-binding pocket and the substrate lysine tunnel of SMYD3. GSK2807 may be useful for cancer treatment.

Histone Methyltransferase, Others

Chromatin/Epigenetic, Others

2245186

C19H32N8O5

452.51

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN(CC[C@@H](C(O)=O)N)CCCN(C)C)[C@H]1O

-20°C

Ice Packs

Small Compound