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GSK-3β inhibitor 8 - CAS 1139875-74-3
GSK-3β inhibitor 8 - CAS 1139875-74-3
SKU:MF-0042350-01
Regular price
$92.44 USD
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$92.44 USD
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Product Details
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Bioactivity
GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine derivative that negatively regulates the Wnt signaling pathway and stimulates β-cell proliferation.
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Target
GSK-3, Wnt/beta-catenin
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Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Stem Cells
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CAS Number
1139798
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Purity
0.9846
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Molecular Formula
C20H20ClN5OS
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Molecular Weight
413.92
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SMILES
C(=O)(C1=C(Cl)C=C(NC=2N=C(C=CN2)C3=CC=CS3)C=C1)N4CCN(C)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound