Molfinity

GSK 591 dihydrochloride - CAS 2320953-89-5

SKU:MF-0052853

$1,217.08 USD

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Size 10 mg

Product Details

Bioactivity
Potent and selective PRMT5 inhibitor (IC50 = 4 nM) . Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website.
Target
Others, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic, Others
CAS Number
2320859
Molecular Formula
C22H30Cl2N4O2
Molecular Weight
453.41
SMILES
Cl.Cl.O[C@@H](CNC(=O)c1ccnc(NC2CCC2)c1)CN1CCc2ccccc2C1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound