1 1

Molfinity

GSK-843 - CAS 1601496-05-2

GSK-843 - CAS 1601496-05-2

MF-0022467

$146.06 USD
$146.06 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    GSK-843 (GSK'843) is a selective and potent RIP3 inhibitor with an IC50 value of 8.6 nM for the structural domain of RIP3 kinase. It has potential analgesic activity, inhibits the expression of RIP3 and NLRP3 in the SDH of CFA mice, and can be used as adjunctive therapy for treating inflammation.

  • Target

    Apoptosis, RIP kinase

  • Related Pathways

    NF-κB, Apoptosis

  • CAS Number

    1601496-05-2

  • Purity

    0.9918

  • Molecular Formula

    C19H15N5S2

  • Molecular Weight

    377.49

  • SMILES

    Cc1cc(-c2cnc(N)c3c(csc23)-c2ccc3scnc3c2)n(C)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound