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GSK 872 hydrochloride - CAS 2703752-81-0
GSK 872 hydrochloride - CAS 2703752-81-0
SKU:MF-0093635-01
Regular price
$33.17 USD
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$33.17 USD
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Product Details
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Bioactivity
GSK872 HCl (1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM) .
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Target
RIP kinase
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Related Pathways
NF-κB, Apoptosis
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CAS Number
2703671
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Purity
0.9982
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Molecular Formula
C19H18ClN3O2S2
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Molecular Weight
419.94
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SMILES
Cl.CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound