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Molfinity

GSK-J1 - CAS 1373422-53-7

GSK-J1 - CAS 1373422-53-7

SKU:MF-0014814-01

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  • Bioactivity

    GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.

  • Target

    Histone Demethylase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    1373362

  • Purity

    0.9967

  • Molecular Formula

    C22H23N5O2

  • Molecular Weight

    389.45

  • SMILES

    OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound