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GSK-J4 - CAS 1373423-53-0
GSK-J4 - CAS 1373423-53-0
SKU:MF-0017625-01
Regular price
$48.12 USD
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$48.12 USD
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Product Details
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Bioactivity
GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A (IC50=8.6/6.6 μM) . GSK-J4 induces endoplasmic reticulum stress-related apoptosis.
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Target
Histone Demethylase, Apoptosis
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Related Pathways
Chromatin/Epigenetic, Apoptosis
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CAS Number
1373370
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Purity
0.9998
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Molecular Formula
C24H27N5O2
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Molecular Weight
417.5
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SMILES
CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound