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Molfinity

GSK-J4 - CAS 1373423-53-0

GSK-J4 - CAS 1373423-53-0

SKU:MF-0017625-01

Regular price $48.12 USD
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  • Bioactivity

    GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A (IC50=8.6/6.6 μM) . GSK-J4 induces endoplasmic reticulum stress-related apoptosis.

  • Target

    Histone Demethylase, Apoptosis

  • Related Pathways

    Chromatin/Epigenetic, Apoptosis

  • CAS Number

    1373370

  • Purity

    0.9998

  • Molecular Formula

    C24H27N5O2

  • Molecular Weight

    417.5

  • SMILES

    CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound