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GSK SYK inhibitor - CAS 1345461-77-9

GSK SYK inhibitor - CAS 1345461-77-9

SKU:MF-0145227-01

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  • Bioactivity

    The immunoregulator spleen tyrosine kinase (SYK) is upregulated in cutaneous lupus erythematosus (CLE) . This double-blind, multicentre, Phase Ib study evaluated the safety, tolerability, pharmacokinetics, pharmacodynamics and clinical efficacy of the selective SYK inhibitor GSK2646264 in active CLE lesions

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1345375

  • Molecular Formula

    C21H27FN6

  • Molecular Weight

    382.48

  • SMILES

    N(CC1(F)CCCNC1)C=2C3=C(C=C(N2)C4=CN(C(C)(C)C)N=C4)N=CC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound