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Molfinity

GSK180736A - CAS 817194-38-0

GSK180736A - CAS 817194-38-0

MF-0016915-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), but highly effective against ROCK1 (IC50: 100 nM) .

  • Target

    ROCK, GRK, PKA

  • Related Pathways

    GPCR/G Protein, Stem Cells, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

  • CAS Number

    817156

  • Purity

    0.9898

  • Molecular Formula

    C19H16FN5O2

  • Molecular Weight

    365.36

  • SMILES

    CC1=C(C(NC(=O)N1)c1ccc(F)cc1)C(=O)Nc1ccc2[nH]ncc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound