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GSK1838705A - CAS 1116235-97-2
GSK1838705A - CAS 1116235-97-2
SKU:MF-0093241-01
Regular price
$35.41 USD
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$35.41 USD
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Product Details
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Bioactivity
GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.
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Target
JNK, ALK, IGF-1R, S6 Kinase
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Related Pathways
MAPK, PI3K/Akt/mTOR signaling, Angiogenesis, Tyrosine Kinase/Adaptors
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CAS Number
1116136
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Purity
>99.99%
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Molecular Formula
C27H29FN8O3
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Molecular Weight
532.57
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SMILES
CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound