GSK2239633 - CAS 2181665-31-4

GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2 T-helper lymphocytes to the inflamed airways. Therefore, CCR4 provides an excellent target for anti-inflammatory therapy.

Others

Others

2181630

C21H19ClN4O5S2

506.98

N(S(=O)(=O)C=1SC(Cl)=CC1)C=2C=3C(N(CC4=CC(NC(CO)=O)=CC=C4)N2)=CC=CC3OC

-20°C

Ice Packs

Small Compound