GSK2245035 - CAS 1207629-49-9

GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN) -stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα) . It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures.

Others, TNF, IFNAR, TLR

Apoptosis, Immunology/Inflammation, Others

1207571

C20H34N6O2

390.52

CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCCN3CCCCC3)c2n1

-20°C

Ice Packs

Small Compound