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GSK248233A - CAS 850665-21-3
GSK248233A - CAS 850665-21-3
SKU:MF-0120684-01
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Product Details
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Bioactivity
GSK248233A is a dual inhibitor targeting Fluc and VEGFR2, exhibiting IC50 values of 1.03 μM and 2 nM, respectively. Additionally, it demonstrates activity against the AGC family and functions as a protein kinase inhibitor for both ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].
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Target
VEGFR, Others
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Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Others
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CAS Number
850665-21-3
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Molecular Formula
C25H24N8O3
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Molecular Weight
484.51
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SMILES
C(C)N1C=2C(N=C1C3=NON=C3N)=CN=C(OC4=CC(NC(=O)C5=CC=C(N(C)C)C=C5)=CC=C4)C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound