GSK256066 - CAS 801312-28-7

GSK256066 is a selective PDE4B (equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.

PDE

Metabolism

801312-28-7

0.9966

C27H26N4O5S

518.58

N(C=1C2=C(C(C)=CC(S(=O)(=O)C3=CC(C(N(C)C)=O)=CC=C3)=C2)N=CC1C(N)=O)C4=CC(OC)=CC=C4

-20°C

Ice Packs

Small Compound