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Molfinity

GSK2606414 - CAS 1337531-36-8

GSK2606414 - CAS 1337531-36-8

MF-0019511-01

$55.60 USD
$55.60 USD
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Product Details

  • Bioactivity

    GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase (PERK) inhibitor with IC50 of 0.4 nM. GSK2606414 inhibits PERK activation in cells and suppresses the growth of human tumor xenografts in mice.

  • Target

    PERK, Autophagy, Apoptosis

  • Related Pathways

    Apoptosis, Autophagy

  • CAS Number

    1337487

  • Purity

    >99.99%

  • Molecular Formula

    C24H20F3N5O

  • Molecular Weight

    451.44

  • SMILES

    NC1=C2C(=CN(C)C2=NC=N1)C=3C=C4C(=CC3)N(C(CC5=CC(C(F)(F)F)=CC=C5)=O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound