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GSK2945 - CAS 1438071-12-5
GSK2945 - CAS 1438071-12-5
SKU:MF-0022479-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
GSK2945 is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM) . It enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.
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Target
Cytochromes P450, Others
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Related Pathways
Others, Metabolism
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CAS Number
1438054
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Molecular Formula
C20H18Cl2N2O2S
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Molecular Weight
421.34
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SMILES
N(CC=1SC(N(=O)=O)=CC1)(CC2=C(C)C=C(Cl)C=C2)CC3=CC=C(Cl)C=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound