GSK3-IN-10 - CAS 844441-56-1

GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3α and GSK3β with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of β-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.

GSK-3, JNK, DYRK, Others, CDK, Wnt/beta-catenin

Tyrosine Kinase/Adaptors, MAPK, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Others, Stem Cells, Cytoskeletal Signaling

844384

C17H18F2N4O3

364.347

O=C(NCC1CCOCC1)C2=NNC=C2NC(=O)C=3C(F)=CC=CC3F

-20°C

Ice Packs

Small Compound