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Molfinity

GSK3527497 HCl - CAS 2215855-51-7

GSK3527497 HCl - CAS 2215855-51-7

MF-0144318-01

$2,041.92 USD
$2,041.92 USD
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Product Details

  • Bioactivity

    GSK3527497 is a potent and selective inhibitor of Transient Receptor Potential Vanilloid‐4 (TRPV4) with IC50 = 12 nM) for the treatment of heart failure and respiratory diseases. GSK3527497 is a preclinical candidate suitable for oral and iv administration that is projected to inhibit TRPV4 effectively in patients from a low daily clinical dose.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    2215797

  • Molecular Formula

    C17H17Cl2FN4O4S

  • Molecular Weight

    463.3054

  • SMILES

    Cl.NC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cn1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound