GSK3739936 - CAS 1803444-21-4

GSK3739936 is a potent inhibitor of HIV-1 allosteric integrase (IC50: 11.1 nM, EC50: 1.7 nM) . GSK3739936 is also a weak inhibitor of CYP with an IC50 >24.3 μM. It has good pharmacokinetic properties with rapid absorption, low to moderate clearance and good oral bioavailability.

Others, HIV Protease

Proteases/Proteasome, Microbiology/Virology, Others

1803419

C34H43FN2O4

562.71

[C@@H](OC(C)(C)C)(C(O)=O)C1=C(C(=C(C)N=C1C)C2=CC=C(OCCC3=CC=C(F)C=C3)C=C2)N4CCC(C)(C)CC4

-20°C

Ice Packs

Small Compound