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Molfinity

GSK563 - CAS 1983928-04-6

GSK563 - CAS 1983928-04-6

SKU:MF-0144495-01

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  • Bioactivity

    GSK563 is a potent GVIA iPLA2 inhibitor (XI (50) 0.0000021, IC50 1 nM) . GSK563 is 22 000 times more active against GVIA iPLA2 than GIVA cPLA2. It was found to reduce β-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1983928-04-6

  • Molecular Formula

    C16H22O2

  • Molecular Weight

    246.34

  • SMILES

    C(CC)C1C(CCCCC2=CC=CC=C2)C(=O)O1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound