GSM III - CAS 1493797-28-6

GSM III is a modulator of the γ-secretase complex (GSEC) . It significantly influences the length of amyloid β protein (Aβ) at the extracellular interface between the protease components (NCT, PSEN) and the substrate APPC99. GSM III is applied in Alzheimer's disease (AD) research.

Gamma-secretase, Beta Amyloid

Proteases/Proteasome, Stem Cells, Neuroscience

1493763

C24H22F3N5O2

469.46

C(C=1C=2C(N(C)C1)=CC=C(C(F)(F)F)C2)N3C(=O)C=4N(C[C@H]3C)C(=O)C(=CC4)N5C=NC(C)=C5

-20°C

Ice Packs

Small Compound