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Molfinity

GTI 2040 - CAS 236391-66-5

GTI 2040 - CAS 236391-66-5

MF-0120685-01

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Product Details

  • Bioactivity

    GTI-2040, a 20-mer phosphorothioate oligonucleotide, targets the mRNA sequence of human ribonucleotide reductase R2 for hybridization. This compound inhibits cancer cell proliferation by reducing R2 expression in vitro and markedly suppresses tumor growth in xenograft models of human cancer in mice.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair

  • CAS Number

    236391-66-5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound