GTP-14564 - CAS 34823-86-4

GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 μ m, whereas a 30-fold higher concentration of GTP-14564 is required to inhibit the FLT3 ligand-dependent growth (wt-FLT3) of Ba/F3 expressing wild-type FLT3. F3 expressing wild-type FLT3 (wt-FLT3) .

Tyrosine Kinases, FLT

Angiogenesis, Tyrosine Kinase/Adaptors

34733

0.9981

C15H10N2O

234.25

C12=C(C=3C(O1)=CC=CC3)NN=C2C4=CC=CC=C4

-20°C

Ice Packs

Small Compound