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Molfinity
Guajadial B - CAS 1414455-03-0
Guajadial B - CAS 1414455-03-0
SKU:MF-0045980
Regular price
$399.25 USD
Regular price
Sale price
$399.25 USD
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Product Details
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Bioactivity
Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells.
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Target
Topoisomerase
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Related Pathways
DNA Damage/DNA Repair
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CAS Number
1414455-03-0
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Molecular Formula
C30H34O5
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Molecular Weight
474.597
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SMILES
C\C1=C/CC(C)(C)\C=C\C[C@@]2(C)Oc3c(C=O)c(O)c(C=O)c(O)c3[C@H]([C@@H]2CC1)c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product