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Molfinity

Guajadial B - CAS 1414455-03-0

Guajadial B - CAS 1414455-03-0

SKU:MF-0045980

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  • Bioactivity

    Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells.

  • Target

    Topoisomerase

  • Related Pathways

    DNA Damage/DNA Repair

  • CAS Number

    1414455-03-0

  • Molecular Formula

    C30H34O5

  • Molecular Weight

    474.597

  • SMILES

    C\C1=C/CC(C)(C)\C=C\C[C@@]2(C)Oc3c(C=O)c(O)c(C=O)c(O)c3[C@H]([C@@H]2CC1)c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product