Gue1654 - CAS 397290-30-1

Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.Gue1654 inhibits OXE-R-inhibited protein kinase C-ε (PKC-ε) /nuclear factor κB (NF-κB) signaling and apoptosis in cardiomyocytes. Gue1654 can be used to study cardiovascular disease.

Others, PKC, NF-κB

NF-κB, Others, Cytoskeletal Signaling, Chromatin/Epigenetic

397259

0.9831

C23H17N3OS3

447.6

O=C(NC1=NC=2C=CC=3N=C(SC3C2S1)SC)C(C=4C=CC=CC4)C=5C=CC=CC5

-20°C

Ice Packs

Small Compound