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GW-406381 - CAS 221148-46-5
GW-406381 - CAS 221148-46-5
SKU:MF-0012995-01
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Product Details
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Bioactivity
GW-406381 is a highly selective COX-2 inhibitor acting peripherally and centrally, reducing spontaneous ectopic discharges in rat sural nerves following chronic compressive injury. It is suitable for studying central sensitisation and inflammatory pain.
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Target
COX
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Related Pathways
Neuroscience, Immunology/Inflammation
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CAS Number
221097
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Purity
0.9954
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Molecular Formula
C21H19N3O3S
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Molecular Weight
393.46
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SMILES
CCOc1ccc(cc1)-c1nn2ncccc2c1-c1ccc(cc1)S(C)(=O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound