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Molfinity

GW274150 - CAS 210354-22-6

GW274150 - CAS 210354-22-6

MF-0022503-01

$33.92 USD
$33.92 USD
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Product Details

  • Bioactivity

    GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS) .GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.

  • Target

    NOS, NO Synthase

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    210326

  • Purity

    >99.99%

  • Molecular Formula

    C8H17N3O2S

  • Molecular Weight

    219.3

  • SMILES

    C([C@@H](C(O)=O)N)CSCCNC(C)=N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound