GW549390X - CAS 135307-33-4

GW549390X is a dual inhibitor targeting both Fluc and VEGFR2, with IC50 values of 0.26 μM and 1.2 μM, respectively. This compound binds to the ATP pocket of FLuc via the aniline side chain, functioning as an ATP-competitive inhibitor of Fluc. It serves as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially affecting Fluc reporter assays [1].

Others, VEGFR

Others, Angiogenesis, Tyrosine Kinase/Adaptors

135307-33-4

C15H12N2O

236.27

N(C=1OC(=CN1)C2=CC=CC=C2)C3=CC=CC=C3

-20°C

Ice Packs

Small Compound