GW694590A - CAS 948313-24-4

GW694590A (UNC10112731) functions as a MYC protein stabilizer that enhances the levels of endogenous MYC protein. It also acts on receptor tyrosine kinases, inhibiting DDR2, KIT, and PDGFRα by 81%, 68%, and 67% at a concentration of 1 μM, respectively. As a protein kinase inhibitor, GW694590A affects both ATP-dependent and ATP-independent luciferases, potentially influencing the Fluc reporter gene [1].

PDGFR, c-Kit, c-Myc, Discoidin Domain Receptor (DDR)

Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint

948313-24-4

C22H19N5O4

417.42

N(C(OC)=O)C=1NC=2C(N1)=CC=C(OC3=CC=C(NC(NC4=CC=CC=C4)=O)C=C3)C2

-20°C

Ice Packs

Small Compound