GW786034B - CAS 635702-64-6

Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.

PDGFR, c-Kit, VEGFR, FGFR, Autophagy, c-Fms

Autophagy, Angiogenesis, Tyrosine Kinase/Adaptors

635632

0.9987

C21H23N7O2S·HCl

473.98

Cl.CN(C1=CC2=NN(C)C(C)=C2C=C1)C1=NC(NC2=CC=C(C)C(=C2)S(N)(=O)=O)=NC=C1

-20°C

Ice Packs

Small Compound