GW814408X - CAS 886599-05-9

GW814408X, a kinase chemical genome group (KCGS) compound, inhibits the AURKC kinase, which is involved in cell cycle progression, checkpoint regulation, and cell division. It exhibits cell line-dependent toxicity, such as cytotoxic effects on HeLa cells, and acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].

Aurora Kinase, Others

Chromatin/Epigenetic, Others, Cell Cycle/Checkpoint

886599-05-9

C19H16N6O

344.37

N(N=CC=1C=CN=CC1)C2=C3C(C(=CN3)C4=CC(OC)=CC=C4)=NC=N2

-20°C

Ice Packs

Small Compound