GW8510 - CAS 222036-17-1

GW8510 is a CDK2 (cell cycle protein-dependent kinase 2) inhibitor and RRM2 (Ribonucleotide Reductase Regulatory Subunit M2) inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 improves cognition and prolongs lifespan, which may be related to the modulation of the expression of cell cycle-related protein p21 and CDK family genes, as well as the improvement of mitochondrial function.

DNA/RNA Synthesis, CDK

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

222018

0.9932

C21H15N5O3S2

449.51

O=C1NC=2C=CC=3N=CSC3C2C1=CNC4=CC=C(C=C4)S(=O)(=O)NC5=NC=CC=C5

-20°C

Ice Packs

Small Compound