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H-1152 - CAS 451462-58-1
H-1152 - CAS 451462-58-1
SKU:MF-0020151-01
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Product Details
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Bioactivity
H-1152 is a cell membrane-permeable and selective ROCK (Rho-kinase) inhibitor (Ki=1.6 nM) that increases neurite length in neuron-rich cultures and inhibits MARCKS Ser159 phosphorylation in LPA-stimulated neuronal cells.
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Target
ROCK
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Related Pathways
Cell Cycle/Checkpoint, Stem Cells, Cytoskeletal Signaling
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CAS Number
451462-58-1
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Molecular Formula
C16H21N3O2S
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Molecular Weight
319.42
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SMILES
S(=O)(=O)(C=1C2=C(C=CC1)C=NC=C2C)N3[C@@H](C)CNCCC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound