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H-1152 dihydrochloride - CAS 871543-07-6

H-1152 dihydrochloride - CAS 871543-07-6

MF-0014062-01

$53.35 USD
$53.35 USD
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Product Details

  • Bioactivity

    H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.

  • Target

    ROCK

  • Related Pathways

    Cytoskeletal Signaling, Cell Cycle/Checkpoint, Stem Cells

  • CAS Number

    871543-07-6

  • Purity

    0.9985

  • Molecular Formula

    C16H23Cl2N3O2S

  • Molecular Weight

    392.34

  • SMILES

    Cl.Cl.C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(C)c12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound