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H3R antagonist 5 - CAS 879368-27-1
H3R antagonist 5 - CAS 879368-27-1
SKU:MF-0113922-01
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Product Details
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Bioactivity
H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.
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Target
Histamine Receptor
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Related Pathways
Neuroscience, Immunology/Inflammation, GPCR/G Protein
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CAS Number
879340
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Molecular Formula
C23H32N2O4
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Molecular Weight
400.511
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SMILES
O=C1O[C@]2(C=3C1=CC(OC)=CC3)CC[C@@H](C(N(CCN4CCCCC4)C)=O)CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound