HA2A/hCA XII modulator 1 - CAS 2548963-55-7

HA2A/hCA XII modulator 1 is a potent antagonist of the hA2A adenosine receptor (hA2AAR), a triazolopyrazine that acts on hA2AAR (Ki: 6.4 nM), hA1AR (Ki: 4.819 μM), and hA3AR (Ki>30 μM) . hA2A/hCA XII modulator 1 Also a potent inhibitor of human carbonic anhydrase XII (hCA XII), capable of acting on hCA XII (Ki: 6.2 nM), hCA II (Ki: 46 nM), hCA IX (Ki: 466 nM) and hCA I (Ki: 8.351 μM) . hA2A/hCA XII modulator 1 exhibits potential for cancer research.

Carbonic Anhydrase, Others, Adenosine Receptor

GPCR/G Protein, Neuroscience, Metabolism, Others

2548901

C24H19N7O4S

501.52

O=C1N2C(=NN1C3=CC=CC=C3)C(N)=NC(=C2)C4=CC=C(NC(=O)C5=CC=C(S(N)(=O)=O)C=C5)C=C4

-20°C

Ice Packs

Small Compound