Hainantoxin-III - CAS 1809149-40-3

Jingzhaotoxin-V is a peptide that suppresses potassium currents in Xenopus laevis oocytes with an IC50 of 604.2 nM, while targeting both tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC50 values of 27.6 nM and 30.2 nM, respectively [1].

Sodium Channel

Membrane transporter/Ion channel

1809106

C154H228N44O45S6

3608.12

C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)[C@@H](C)C)=O)CCCCN)=O)CSSC[C@]5(C(=O)N[C@@]6(C(=O)N7[C@](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC8=CC=C(O)C=C8)C(=O)N[C@@H](C)C(=O)N[C@](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC9=CN=CN9)C(=O)N[C@@H](CCCCN)C(=O)N3)(CSSCC(C(=O)N[C@@]([C@@H](C)O)(C(=O)N%10[C@](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N5)(CCC%10)[H])[H])(NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC%11=CC=CC=C%11)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(CN)=O)CSSC6)[H])[H])(CCC7)[H])[H])[H]

-20°C

Ice Packs

Peptide