HB-0017 - CAS 2790610-50-1

HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor that targets IL-17A. It effectively blocks IL-17A-induced IL-6 secretion with an IC50 of 2.09 nM. In psoriatic-like mouse models induced by Imiquimod, HB-0017 significantly reduces auricular thickness and alleviates inflammation in arthritis and air pouch mouse models caused by IL-17A. For isotype control, refer to Human IgG1 kappa, Isotype Control.

Interleukin

Immunology/Inflammation

2790610-50-1

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Ice Packs

Inhibitory Antibodies