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HBX 41108 - CAS 924296-39-9
HBX 41108 - CAS 924296-39-9
SKU:MF-0013461-01
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$35.41 USD
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$35.41 USD
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Product Details
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Bioactivity
HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
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Target
Apoptosis, MDM-2/p53, DUB, p53
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Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination, Apoptosis
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CAS Number
924248
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Purity
0.9965
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Molecular Formula
C13H3ClN4O
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Molecular Weight
266.64
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SMILES
Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound