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Molfinity

HBX 41108 - CAS 924296-39-9

HBX 41108 - CAS 924296-39-9

SKU:MF-0013461-01

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  • Bioactivity

    HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.

  • Target

    Apoptosis, MDM-2/p53, DUB, p53

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination, Apoptosis

  • CAS Number

    924248

  • Purity

    0.9965

  • Molecular Formula

    C13H3ClN4O

  • Molecular Weight

    266.64

  • SMILES

    Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound