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HCAI/II-IN-2 - CAS 2480283-75-6
HCAI/II-IN-2 - CAS 2480283-75-6
SKU:MF-0140366-01
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$1,383.80 USD
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Product Details
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Bioactivity
HCAI/II-IN-2 (compound 2b) is a highly effective dual inhibitor of human carbonic anhydrase I and II (hCA I/II), with Ki values of 40.97 nM for hCA I, 15.15 nM for hCA II, and 61.88 nM for hCA IX. With its anti-hypoxic properties, hCAI/II-IN-2 demonstrates activity against acute mountain sickness (AMS) and exhibits low cellular activity [1].
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Target
Others, Carbonic Anhydrase
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Related Pathways
Metabolism, Others
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CAS Number
2480202
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Molecular Formula
C12H12N4O5S2
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Molecular Weight
356.38
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SMILES
N(C(=O)C1=CC=C(S(N)(=O)=O)C=C1)C=2SC(C(OCC)=O)=NN2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound