HCAI/II-IN-8 - CAS 3036136-18-9

HCAI/II-IN-8 (Compound 8) is a hydrazone derivative originating from 4-hydroxybenzaldehyde. It primarily inhibits human carbonic anhydrase isoenzymes I (hCA I) and II (hCA II) with IC50 values of 21.35 ± 0.39 nM for hCA I and 7.12 ± 0.12 nM for hCA II. It also exhibits inhibitory effects on AChE and BChE, with IC50 values of 46.27 ± 0.75 nM and 43.38 ± 0.83 nM, respectively.

Cholinesterase (ChE), Carbonic Anhydrase

Neuroscience, Metabolism

3036109

C22H20N4O3

388.42

O=C(OC1=CC=C(C=NNC(=O)C=2C=NC=CC2)C=C1)C3=CC=C(C=C3)N(C)C

-20°C

Ice Packs

Small Compound