HCAIX-IN-10 - CAS 2497504-72-8

HCAIX-IN-10 (Compound 6i) is a selective inhibitor of carbonic anhydrase IX and XII, targeting hCA IX (Ki: 61.5 nM) and hCA XII (Ki: 586.8 nM) . hCA IX and hCA XII are transmembrane isoforms of carbonic anhydrase and serve as biomarkers for certain types of tumors, with hCA XII also playing a role in maintaining acid-base homeostasis in both normal and tumor cells.

Others, Carbonic Anhydrase

Metabolism, Others

2497504-72-8

C28H21N3O3S

479.55

O=C1C(C=2C(=CN(N2)C3=CC=CC=C3)C4N(C(=O)CS4)C5=CC(C)=CC=C5)=CC=6C(O1)=CC=CC6

-20°C

Ice Packs

Small Compound