HCAIX-IN-12 - CAS 2414598-85-7

HCAIX-IN-12 is an effective hCAIX inhibitor, IC50 for CAIX and CAII is 0.74 and 10.78 μM , respectively. hCAIX-IN-12 inhibits cell proliferation and induces apoptosis. HCAIX-IN-12 can increase the generation of ROS. HCAIX-IN-12 has research potential in colorectal cancer (CRC) .

Carbonic Anhydrase, Reactive Oxygen Species, Apoptosis, Others

NF-κB, Others, Apoptosis, Metabolism, Immunology/Inflammation

2414506

C18H14N4O3S2

398.46

N(S(=O)(=O)C1=CC=C(N)C=C1)C2=C(SC=C2)C3=NC(=NO3)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound